Retinoic Acid Receptor gamma antibody (N-Term)

Catalog No. ABIN5688663

This Mouse Monoclonal antibody specifically detects Retinoic Acid Receptor gamma in WB. It exhibits reactivity toward Human, Mouse, Dog and Cow.

Quick Overview for Retinoic Acid Receptor gamma antibody (N-Term) (ABIN5688663)

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Reactivity: Human, Mouse, Dog, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoic Acid Receptor gamma antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 763

Product Details anti-Retinoic Acid Receptor gamma Antibody

Binding Specificity: N-Term

Purification: Protein G purified

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of human retinoic acid receptor, a-isotype.

Isotype: IgG1

Application Details

Application Notes: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, canine and mouse tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Retinoic Acid Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for Retinoic Acid Receptor gamma

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Alternative Name: Retinoic Acid Receptor

Background: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRalpha, beta and gamma), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Molecular Weight: 48 kDa

Gene ID: 5914

UniProt: P10276

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size