NEFL
Reactivity: Pig
WB, IF
Host: Mouse
Monoclonal
DA2
unconjugated
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Storage
-20 °C
Storage Comment
Neurofilament NF-L antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
Target
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Alternative Name
Neurofilament NF-L
Background
Neurofilaments are the 10nm or intermediate filament proteins specifically in neurons, and are composed predominantly of three major proteins called NF- NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.