Rabphilin antibody (pSer234)

Catalog No. ABIN5688892

The Rabbit Polyclonal anti-Rabphilin antibody has been validated for IHC and WB. It is suitable to detect Rabphilin in samples from Mouse and Rat.

Quick Overview for Rabphilin antibody (pSer234) (ABIN5688892)

Target: Rabphilin (RPH)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-Rabphilin Antibody

Binding Specificity: pSer234

Purification: Affinity Purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser234 of rabphilin 3A.

Application Details

Application Notes: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse based on the fact that this species has 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Rabphilin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for Rabphilin

Target: Rabphilin (RPH)

Alternative Name: Rabphilin

Background: Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994,Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington's disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995,Foletti and Scheller, 2001).

Molecular Weight: 82 kDa

Gene ID: 171039

UniProt: P47709