TAO Kinase 2 antibody (pSer181)

Catalog No. ABIN5688917

This anti-TAO Kinase 2 antibody is a Rabbit Polyclonal antibody detecting TAO Kinase 2 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for TAO Kinase 2 antibody (pSer181) (ABIN5688917)

Target: TAO Kinase 2 (TAOK2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAO Kinase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TAO Kinase 2 Antibody

Binding Specificity: pSer181

Specificity: TAO2 antibody is specific for Mr ~120k TAO2 phosphorylated at Ser181.

Purification: Affinity Purified

Immunogen: TAO2 (Ser181) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser181 of TAO2.

Application Details

Application Notes: Human, mouse, rat and Xenopus have 100 % amino acid sequence identity with the antigen used to raise the antibody. Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not been determined. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.

Target Details for TAO Kinase 2

Target: TAO Kinase 2 (TAOK2)

Alternative Name: TAO2

Background: TAO (thousand and one amino acid) protein kinases mediate signaling from carbachol to p38 MAPK and ternary complex transcription factors. This has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPKs. Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.

Molecular Weight: 120 kDa

Gene ID: 9344

UniProt: Q9UL54

Pathways: Cell-Cell Junction Organization