ADIPOQ antibody (AA 235-239)
Quick Overview for ADIPOQ antibody (AA 235-239) (ABIN5689238)
Target
See all ADIPOQ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 235-239
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Specificity
- This antibody detects endogenous level of total Adiponectin protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- Adiponectin antibody was raised against a peptide sequence around aa.235~239 (T-G-F-L-L) derived from Human Adiponectin.
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Application Notes
- Western Blot: 1:500~1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store antibody at -20°C for up to one year.
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- ADIPOQ (Adiponectin (ADIPOQ))
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Alternative Name
- Adiponectin
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Background
- Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-κ,-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
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Molecular Weight
- 27 kDa
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Gene ID
- 9370
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NCBI Accession
- NP_001171271
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UniProt
- Q15848
Target
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