Histone H3.1 antibody (AA 8-12)

Catalog No. ABIN5689294

The Rabbit Polyclonal anti-Histone H3.1 antibody has been validated for WB and IF. It is suitable to detect Histone H3.1 in samples from Human, Mouse and Rat.

Quick Overview for Histone H3.1 antibody (AA 8-12) (ABIN5689294)

Target: Histone H3.1 (HIST1H3B)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H3.1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Histone H3.1 Antibody

Binding Specificity: AA 8-12

Specificity: This antibody detects endogenous level of total Histone H3.1 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Histone H3.1 (Ab-10) antibody was raised against a peptide sequence around aa.8~12 (R-K-S-T-G) derived from Human Histone H3.1.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for Histone H3.1

Target: Histone H3.1 (HIST1H3B)

Alternative Name: Histone H3.1

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Molecular Weight: 17 kDa

Gene ID: 8351

NCBI Accession: NP_003521

UniProt: P68431