PK (AA 449-453) antibody

Catalog No. ABIN5689314

This Rabbit Polyclonal antibody specifically detects PK in IF and IHC. It exhibits reactivity toward Human.

Quick Overview for PK (AA 449-453) antibody (ABIN5689314)

Target: PK

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 449-453

Specificity: This antibody detects endogenous level of total PKR protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: PKR (Ab-451) antibody was raised against a peptide sequence around aa.449~453 (K-G-T-L-R) derived from Human PKR.

Application Details

Application Notes: Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details

Target: PK

Background: Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

Molecular Weight: 68 kDa

Gene ID: 5610

NCBI Accession: NP_001129123

UniProt: P19525