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c-FOS antibody (AA 28-32)

This anti-c-FOS antibody is a Rabbit Polyclonal antibody detecting c-FOS in WB. Suitable for Human, Rat and Mouse.
Catalog No. ABIN5689379

Quick Overview for c-FOS antibody (AA 28-32) (ABIN5689379)

Target

See all c-FOS (c-Fos) Antibodies
c-FOS (c-Fos) (c-Fos)

Reactivity

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Human, Rat, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This c-FOS antibody is un-conjugated

Application

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Western Blotting (WB)
  • Binding Specificity

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    AA 28-32

    Specificity

    This antibody detects endogenous level of total C-Fos protein.

    Purification

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    Immunogen

    C-Fos antibody was raised against a peptide sequence around aa.28~32 ( S-Y-Y-H-S) derived from Human C-Fos.
  • Application Notes

    Western Blot: 1:500~1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store antibody at -20°C for up to one year.
  • Target

    c-FOS (c-Fos) (c-Fos)

    Alternative Name

    C Fos

    Background

    Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

    Molecular Weight

    62 kDa

    Gene ID

    2353

    NCBI Accession

    NP_005243

    UniProt

    P01100

    Pathways

    S100 Proteins
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