c-FOS antibody (AA 28-32)

Catalog No. ABIN5689379

The Rabbit Polyclonal anti-c-FOS antibody (ABIN5689379) specifically detects c-FOS in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for c-FOS antibody (AA 28-32) (ABIN5689379)

Target: c-FOS (c-Fos) (c-Fos)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-FOS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-c-FOS Antibody

Binding Specificity: AA 28-32

Specificity: This antibody detects endogenous level of total C-Fos protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: C-Fos antibody was raised against a peptide sequence around aa.28~32 ( S-Y-Y-H-S) derived from Human C-Fos.

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Alternative Name: C Fos

Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

Molecular Weight: 62 kDa

Gene ID: 2353

NCBI Accession: NP_005243

UniProt: P01100

Pathways: S100 Proteins