c-FOS antibody (AA 28-32)
Quick Overview for c-FOS antibody (AA 28-32) (ABIN5689379)
Target
See all c-FOS (c-Fos) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 28-32
-
Specificity
- This antibody detects endogenous level of total C-Fos protein.
-
Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
Immunogen
- C-Fos antibody was raised against a peptide sequence around aa.28~32 ( S-Y-Y-H-S) derived from Human C-Fos.
-
-
-
-
Application Notes
- Western Blot: 1:500~1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store antibody at -20°C for up to one year.
-
-
- c-FOS (c-Fos) (c-Fos)
-
Alternative Name
- C Fos
-
Background
- Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
-
Molecular Weight
- 62 kDa
-
Gene ID
- 2353
-
NCBI Accession
- NP_005243
-
UniProt
- P01100
-
Pathways
- S100 Proteins
Target
-