MME antibody (AA 6-10)

Catalog No. ABIN5689436

This anti-MME antibody is a Rabbit Polyclonal antibody detecting MME in WB. Suitable for Human, Mouse and Rat.

Quick Overview for MME antibody (AA 6-10) (ABIN5689436)

Target: MME (Membrane Metallo-Endopeptidase (MME))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MME antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MME Antibody

Binding Specificity: AA 6-10

Specificity: This antibody detects endogenous level of total CD10 protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: CD10 antibody was raised against a peptide sequence around aa.6~10 (S-Q-M-D-I) derived from Human CD10.

Application Details

Application Notes: Western Blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for MME

Target: MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name: CD10

Target Type: Chemical

Background: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Molecular Weight: 100 kDa

Gene ID: 4311

NCBI Accession: NP_000893

UniProt: P08473

Pathways: RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration