CRY1 antibody (AA 551-555)
Quick Overview for CRY1 antibody (AA 551-555) (ABIN5689445)
Target
See all CRY1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 551-555
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Specificity
- This antibody detects endogenous level of total CRY1 protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- CRY1 antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.
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Application Notes
- Western Blot: 1:500~1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store antibody at -20°C for up to one year.
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- CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))
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Alternative Name
- CRY1
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Background
- Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
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Molecular Weight
- 60 kDa
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Gene ID
- 12952
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NCBI Accession
- NP_031797
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UniProt
- Q16526
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Pathways
- Response to Water Deprivation, Proton Transport
Target
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