DOK2 antibody (AA 297-301)
Quick Overview for DOK2 antibody (AA 297-301) (ABIN5689451)
Target
See all DOK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 297-301
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Specificity
- This antibody detects endogenous level of total p56Dok-2 protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- p56Dok-2 (Ab-299) antibody was raised against a peptide sequence around aa.297~301 (G-E-Y-A-V) derived from Human p56Dok-2.
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Application Notes
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store antibody at -20°C for up to one year.
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- DOK2
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Alternative Name
- p56Dok 2
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Background
- DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
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Molecular Weight
- 56 kDa
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Gene ID
- 9046
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NCBI Accession
- NP_003965
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UniProt
- O60496
Target
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