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ABL1/2 antibody (pTyr393, pTyr429)

ABL1/ABL2 Reactivity: Human, Mouse IHC, WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5689742
  • Target See all ABL1/2 (ABL1/ABL2) Antibodies
    ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
    Binding Specificity
    • 11
    • 10
    • 7
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr393, pTyr429
    Reactivity
    • 24
    • 24
    • 8
    • 1
    Human, Mouse
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ABL1/2 antibody is un-conjugated
    Application
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
    Specificity
    This antibody detects endogenous level of ABL1/2 only when phosphorylated at tyrosine393/429.
    Purification
    Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
    Immunogen
    ABL1/2 (phospho-Tyr393/429) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 393/429 (D-T-Y (p) -T-A) derived from Human ABL1/2.
    Top Product
    Discover our top product ABL1/ABL2 Primary Antibody
  • Application Notes
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store antibody at -20°C for up to one year.
  • Target
    ABL1/2 (ABL1/ABL2) (Abelson Murine Leukemia Viral Oncogene Homolog 1/2 (ABL1/ABL2))
    Alternative Name
    ABL1 / 2 (ABL1/ABL2 Products)
    Synonyms
    CABL antibody, ABLL antibody, cb272 antibody, ABL proto-oncogene 2, non-receptor tyrosine kinase antibody, c-abl oncogene 2, non-receptor tyrosine kinase antibody, ABL2 antibody, abl2 antibody
    Background
    Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
    Molecular Weight
    210 kDa
    Gene ID
    25, 27
    NCBI Accession
    NP_005148, NP_001129472
    UniProt
    P00519, P42684
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