DDX41 antibody (AA 230-280)

Catalog No. ABIN5689942

The Rabbit Polyclonal anti-DDX41 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect DDX41 in samples from Human, Mouse and Rat.

Quick Overview for DDX41 antibody (AA 230-280) (ABIN5689942)

Target: DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX41 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DDX41 Antibody

Binding Specificity: AA 230-280

Specificity: At least two isoforms of DDX41 are known to exist, this antibody will detect both isoforms.

Purification: DDX41 Antibody is affinity chromatography purified via peptide column.

Immunogen: DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41.

The immunogen is located within amino acids 230 - 280 of DDX41.

Isotype: IgG

Application Details

Application Notes: DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: DDX41 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: DDX41 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for DDX41

Target: DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))

Alternative Name: DDX41

Background: DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.

Molecular Weight: Predicted: 68 kDa

Observed: 70 kDa

Gene ID: 51428

NCBI Accession: NP_057306

UniProt: Q9UJV9