KANK3 antibody (AA 50-100)

Catalog No. ABIN5690026

The Rabbit Polyclonal anti-KANK3 antibody is suitable to detect KANK3 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC (p).

Quick Overview for KANK3 antibody (AA 50-100) (ABIN5690026)

Target: KANK3 (KN Motif and Ankyrin Repeat Domains 3 (KANK3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KANK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KANK3 Antibody

Binding Specificity: AA 50-100

Specificity: Two alternatively spliced transcript variants encoding different isoforms have been identified.

Purification: KANK3 Antibody is affinity chromatography purified via peptide column.

Immunogen: KANK3 antibody was raised against an 18 amino acid peptide near the amino terminus of human KANK3 .

The immunogen is located within amino acids 50 - 100 of KANK3.

Isotype: IgG

Application Details

Application Notes: KANK3 Antibody can be used for detection of KANK3 by Western blot starting at 1 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: KANK3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: KANK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for KANK3

Target: KANK3 (KN Motif and Ankyrin Repeat Domains 3 (KANK3))

Alternative Name: KANK3

Background: KANK3 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.

Molecular Weight: Predicted: 90 kDa

Observed: 100 kDa

Gene ID: 256949

NCBI Accession: NP_940873

UniProt: Q6NY19