POU2F3 antibody (AA 370-420)

Catalog No. ABIN5690103

This Rabbit Polyclonal antibody specifically detects POU2F3 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for POU2F3 antibody (AA 370-420) (ABIN5690103)

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU2F3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-POU2F3 Antibody

Binding Specificity: AA 370-420

Specificity: POU2F3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.

Purification: POU2F3 antibody is affinity chromatography purified via peptide column.

Immunogen: POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3.

The immunogen is located within amino acids 370 - 420 of POU2F3.

Isotype: IgG

Application Details

Application Notes: POU2F3 antibody can be used for detection of POU2F3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: POU2F3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: POU2F3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for POU2F3

Target: POU2F3 (POU Class 2 Homeobox 3 (POU2F3))

Alternative Name: POU2F3

Background: POU2F3, also known as Epoc-1, is a member of a family of POU domain family of transcription factors (1). POU2F3 is expressed primarily in the epidermis and plays a critical role in keratinocyte proliferation and differentiation (1,2). It is a crucial transcription factor that is required for the development of sweet, umami, and bitter, but not sour taste receptor cells (3). POU2F3 is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer (4).

Molecular Weight: Predicted: 48 kDa

Observed: 55 kDa

Gene ID: 25833

NCBI Accession: NP_001231611

UniProt: Q9UKI9