Sin Nombre Virus Glycoprotein 2 (AA 670-720) antibody

Catalog No. ABIN5690245

The Rabbit Polyclonal anti-Sin Nombre Virus Glycoprotein 2 antibody is suitable to detect Sin Nombre Virus Glycoprotein 2 in samples from Virus. It has been validated for ELISA.

Quick Overview for Sin Nombre Virus Glycoprotein 2 (AA 670-720) antibody (ABIN5690245)

Target: Sin Nombre Virus Glycoprotein 2

Reactivity: Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA

Product Details

Binding Specificity: AA 670-720

Purification: Sin Nombre virus glycoprotein 2 antibody is affinity chromatography purified via peptide column.

Immunogen: Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein.

The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2.

Isotype: IgG

Application Details

Application Notes: Sin Nombre virus glycoprotein 2 antibody can detect 10 ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Sin Nombre Glycoprotein 2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details

Target: Sin Nombre Virus Glycoprotein 2

Target Type: Viral Protein

Background: Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein.

Gene ID: 2654026

NCBI Accession: NP_941974

UniProt: Q89905