Dermatopontin antibody (AA 19-201)

Catalog No. ABIN5692846

The Rabbit Polyclonal anti-Dermatopontin antibody has been validated for WB and ELISA. It is suitable to detect Dermatopontin in samples from Human, Mouse and Rat.

Quick Overview for Dermatopontin antibody (AA 19-201) (ABIN5692846)

Target: Dermatopontin (DPT)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dermatopontin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Dermatopontin Antibody

Binding Specificity: AA 19-201

Purpose: Anti-Dermatopontin/DPT Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Dermatopontin/DPT Antibody Picoband® (ABIN5692846). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human Dermatopontin recombinant protein (Position: Q19-V201).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: DPT dermatopontin". 2. Kuroda K, Okamoto O, Shinkai H (1999). "Dermatopontin expression is decreased in hypertrophic scar and systemic sclerosis skin fibroblasts and is regulated by transforming growth factor-beta1, interleukin-4, and matrix collagen". J. Invest. Dermatol. 112 (5): 706-10. 3. Superti-Furga A, Rocchi M, Schafer BW, Gitzelmann R (Oct 1993). "Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin)". Genomics. 17 (2): 463-7.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Dermatopontin

Target: Dermatopontin (DPT)

Alternative Name: DPT

Background:

Synonyms: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP, DPT

Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.

Background: Dermatopontin is a protein that in humans is encoded by the DPT gene. Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin.

Molecular Weight: 20 kDa

Gene ID: 1805

UniProt: Q07507