Neuromedin U antibody

Catalog No. ABIN5692905

Product Details anti-Neuromedin U Antibody

Target: Neuromedin U (NMU)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuromedin U antibody is un-conjugated

Application: Western Blotting (WB)

Brand: Picoband™

Sequence: FRVDEEFQSP FASQSRGYFL FRPRN

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human

Characteristics: Rabbit IgG polyclonal antibody for NMU detection. Tested with WB in Human,Mouse,Rat.

Immunogen: A synthetic peptide corresponding to a sequence of human NMU (FRVDEEFQSPFASQSRGYFLFRPRN).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for Neuromedin U

Target: Neuromedin U (NMU)

Alternative Name: NMU (NMU Products)

Background:

Synonyms: Neuromedin-U, Neuromedin-U-25, NmU-25, NMU

Tissue Specificity: Expressed throughout the enteric nervous system with highest levels being found in the jejunum.

Background: Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

UniProt: P48645

Pathways: Feeding Behaviour, Photoperiodism