SATB1 antibody (AA 638-763) (DyLight 488)

Catalog No. ABIN7354604

The Rabbit Polyclonal anti-SATB1 antibody has been validated for FACS. It is suitable to detect SATB1 in samples from Human.

Quick Overview for SATB1 antibody (AA 638-763) (DyLight 488) (ABIN7354604)

Target: SATB1 (SATB Homeobox 1 (SATB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SATB1 antibody is conjugated to DyLight 488

Application: Flow Cytometry (FACS)

Product Details anti-SATB1 Antibody (DyLight 488)

Binding Specificity: AA 638-763

Purpose: Anti-Human SATB1 DyLight® 488 conjugated Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Human SATB1 DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: E. coli-derived human SATB1 recombinant protein (Position: D638-D763).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Galande S, Purbey PK, Notani D, Kumar PP (Oct 2007). "The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1". Current Opinion in Genetics & Development. 17 (5): 408-14. 2. Pavan Kumar P, Purbey PK, Sinha CK, Notani D, Limaye A, Jayani RS, Galande S (Apr 2006). "Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo". Molecular Cell. 22 (2): 231-43.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Target Details for SATB1

Target: SATB1 (SATB Homeobox 1 (SATB1))

Alternative Name: SATB1

Background:

Synonyms: DNA-binding protein SATB1, Special AT-rich sequence-binding protein 1, SATB1

Tissue Specificity: Expressed predominantly in thymus.

Background: The cannabinoid receptor type 1, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

Molecular Weight: 39 kDa

Gene ID: 6304

UniProt: Q01826

Pathways: Caspase Cascade in Apoptosis, Activated T Cell Proliferation