LGALS1/Galectin 1 antibody (AA 2-135)

Catalog No. ABIN5693114

This anti-LGALS1/Galectin 1 antibody is a Rabbit Polyclonal antibody detecting LGALS1/Galectin 1 in ELISA. Suitable for Mouse.

Quick Overview for LGALS1/Galectin 1 antibody (AA 2-135) (ABIN5693114)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGALS1/Galectin 1 antibody is un-conjugated

Application: ELISA

Product Details anti-LGALS1/Galectin 1 Antibody

Binding Specificity: AA 2-135

Purpose: Anti-Galectin 1 Lgals1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Galectin 1 Lgals1 Antibody Picoband® (ABIN5693114). Tested in ELISA applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Galectin 1 recombinant protein (Position: A2-E135).

Isotype: IgG

Application Details

Application Notes: ELISA Capture (Matched Antibody Pair), 2-8 μg/mL
1. Das, K., Lin, Y., Widen, E., Zhang, Y., Scherer, P. E. Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30. Biochem. Biophys. Res. Commun. 280: 1120-1129, 2001. 2. Schaffler, A., Orso, E., Palitzsch, K.-D., Buchler, C., Drobnik, W., Furst, A., Scholmerich, J., Schmitz, G. The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH). Biochem. Biophys. Res. Commun. 260: 416-425, 1999.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Alternative Name: Lgals1

Background:

Synonyms: Galectin-1, Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1, Lgals1, Gbp,

Tissue Specificity: Widespread, most predominant in spleen, lung and prostate.

Background: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Molecular Weight: 15 kDa

Gene ID: 16852

UniProt: P16045

Pathways: Carbohydrate Homeostasis