CD1c antibody (AA 73-287)

Catalog No. ABIN5693174

This anti-CD1c antibody is a Rabbit Polyclonal antibody detecting CD1c in WB. Suitable for Human.

Quick Overview for CD1c antibody (AA 73-287) (ABIN5693174)

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1c antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD1c Antibody

Binding Specificity: AA 73-287

Purpose: Anti-CD1c Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CD1c Antibody Picoband® (ABIN5693174). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human CD1c recombinant protein (Position: K73-L287).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
1. Granelli-Piperno, A., Shimeliovich, I., Pack, M., Trumpfheller, C., Steinman, R. M. HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood. J. Immun. 176: 991-998, 2006. 2. Moody, D. B., Ulrichs, T., Muhlecker, W., Young, D. C., Gurcha, S. S., Grant, E., Rosat, J.-P., Brenner, M. B., Costello, C. E., Besra, G. S., Porcelli, S. A. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature 404: 884-888, 2000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CD1c

Target: CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

Alternative Name: CD1C

Background:

Synonyms: T-cell surface glycoprotein CD1c, CD1c, CD1C

Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.

Background: CD1C is a group-1 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Molecular Weight: 62 kDa

Gene ID: 911

UniProt: P29017