APCS antibody (AA 20-220)

Catalog No. ABIN5693182

The Rabbit Polyclonal anti-APCS antibody has been validated for WB, IHC, ELISA, ICC, IF, FACS. It is suitable to detect APCS in samples from Human.

Quick Overview for APCS antibody (AA 20-220) (ABIN5693182)

Target: APCS (Amyloid P Component, Serum (APCS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APCS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-APCS Antibody

Binding Specificity: AA 20-220

Purpose: Anti-Serum Amyloid P/APCS Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Serum Amyloid P/APCS Antibody Picoband® (ABIN5693182). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human Serum Amyloid P recombinant protein (Position: H20-L220).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. Cathcart ES, Shirahama T, Cohen AS (1967). "Isolation and identification of a plasma component of amyloid". Biochim. Biophy. Acta 147: 392-393. 2. "Entrez Gene: APCS amyloid P component, serum". 3. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP (1994). "Structure of pentameric human serum amyloid P component". Nature 367 (6461): 338-45.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for APCS

Target: APCS (Amyloid P Component, Serum (APCS))

Alternative Name: APCS

Background:

Synonyms: Serum amyloid P-component; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P-component (1-203); APCS; PTX2

Tissue Specificity: Found in serum and urine.

Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

Molecular Weight: 25-29 kDa

Gene ID: 325

UniProt: P02743