GAL antibody

Catalog No. ABIN5693236

The Rabbit Polyclonal anti-GAL antibody has been validated for WB. It is suitable to detect GAL in samples from Mouse and Rat.

Quick Overview for GAL antibody (ABIN5693236)

Target: GAL (Galanin Prepropeptide (GAL))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GAL Antibody

Purpose: Anti-Galanin Antibody Picoband®

Sequence: WTLNSAGYLL GPHAVGNHRS FSDKNGLTS

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human

Characteristics: Anti-Galanin Antibody Picoband® (ABIN5693236). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Galanin, which shares 86.2% amino acid (aa) sequence identity with both mouse and rat Galanin.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
1. Mitsukawa K, Lu X, Bartfai T (June 2008). "Galanin, galanin receptors and drug targets". Cell. Mol. Life Sci. 65 (12): 1796-805. 2. Wu Z, Autry AE, Bergan JF, Watabe-Uchida M, Dulac CG (May 2014)."Galanin neurons in the medial preoptic area govern parental behaviour". Nature. 509 (7500): 325-30.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for GAL

Target: GAL (Galanin Prepropeptide (GAL))

Alternative Name: GAL

Background:

Synonyms: Galanin peptides, Galanin, Galanin message-associated peptide, GMAP, GAL, GAL1, GALN, GLNN

Background: Galanin is a neuropeptide encoded by the GAL gene, that is widely expressed in the brain, spinal cord, and gut of humans as well as other mammals. This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system.

Molecular Weight: 19 kDa

Gene ID: 51083

UniProt: P22466

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Feeding Behaviour