MUC6 antibody (AA 52-230)

Catalog No. ABIN5693243

This anti-MUC6 antibody is a Rabbit Polyclonal antibody detecting MUC6 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for MUC6 antibody (AA 52-230) (ABIN5693243)

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MUC6 Antibody

Binding Specificity: AA 52-230

Purpose: Anti-Gastric Mucin/MUC6 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Gastric Mucin/MUC6 Antibody Picoband® (ABIN5693243). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human Gastric Mucin recombinant protein (Position: H52-R230).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Kwon, J.-A., Lee, S.-Y., Ahn, E.-K., Seol, S.-Y., Kim, M. C., Kim, S. J., Kim, S. I., Chu, I.-S., Leem, S.-H. Short rare MUC6 minisatellites-5 (sic) alleles influence susceptibility to gastric carcinoma by regulating gene expression. Hum. Mutat. 31: 942-949, 2010. 2. Toribara, N. W., Roberton, A. M., Ho, S. B., Kuo, W.-L., Gum, E., Hicks, J. W., Gum, J. R., Jr., Byrd, J. C., Siddiki, B., Kim, Y. S. Human gastric mucin: identification of a unique species by expression cloning. J. Biol. Chem. 268: 5879-5885, 1993.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Alternative Name: MUC6

Background:

Synonyms: Mucin-6, MUC-6, Gastric mucin-6, MUC6

Tissue Specificity: Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.

Background: Mucin 6, oligomeric mucus/gel-forming, also known as MUC6, is a human gene. This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract.

Molecular Weight: 257 kDa

Gene ID: 4588

UniProt: Q6W4X9