TMEM205 antibody (Internal Region)

Catalog No. ABIN569639

The Goat Polyclonal anti-TMEM205 antibody is suitable to detect TMEM205 in samples from Human, Mouse, Rat and Dog. It has been validated for WB and EIA.

Quick Overview for TMEM205 antibody (Internal Region) (ABIN569639)

Target: TMEM205 (Transmembrane Protein 205 (TMEM205))

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This TMEM205 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TMEM205 Antibody

Binding Specificity: AA 137-146, Internal Region

Sequence: C-PDPYRQLREK

Specificity: Recognizes TMEM205 (137-146).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog).
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_212133.1. Genename: TMEM205

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TMEM205

Target: TMEM205 (Transmembrane Protein 205 (TMEM205))

Alternative Name: TMEM205

Background: TMEM205 is a 189 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2 % of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene Bcl-3.Synonyms: Transmembrane protein 205

Molecular Weight: 21.2kDa (NP_212133.1).

Gene ID: 374882

NCBI Accession: NP_212133

UniProt: Q6UW68