Interleukin enhancer-binding factor 3 (ILF3) antibody

Catalog No. ABIN5696831

The Rabbit Polyclonal anti- antibody has been validated for WB, IHC, ELISA, IP and IF. It is suitable to detect in samples from Human, Mouse and Rat.

Quick Overview for Interleukin enhancer-binding factor 3 (ILF3) antibody (ABIN5696831)

Target: Interleukin enhancer-binding factor 3 (ILF3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details

Purpose: ILF3 antibody

Immunogen: interleukin enhancer binding factor 3, 90kDa

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab04288( NF90,ILF3 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details

Target: Interleukin enhancer-binding factor 3 (ILF3)

Alternative Name: ILF3

Background:

Synonyms: Interleukin enhancer-binding factor 3|Double-stranded RNA-binding protein 76 (DRBP76)|M-phase phosphoprotein 4 (MPP4)|Nuclear factor associated with dsRNA (NFAR)|Nuclear factor of activated T-cells 90 kDa (NF-AT-90)|Translational control protein 80 (TCP80)|ILF3|DRBF|MPHOSPH4|NF90

Background: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 90 kDa,110 kDa

Gene ID: 3609

UniProt: Q12906

Pathways: M Phase