UVRAG antibody
Quick Overview for UVRAG antibody (ABIN5697115)
Target
See all UVRAG AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- UV radiation resistance associated gene
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Isotype
- IgG
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Application Notes
- WB :1:500-1:5000,IP:1:200-1:2000,IF:1:10-1:100
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Comment
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HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09352(UVRAG antibody) at dilution of 1:500
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
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Alternative Name
- UVRAG
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Background
- Synonyms:DHTX, p63, UVRAG Background:This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
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Molecular Weight
- 70kDa
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Gene ID
- 7405
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UniProt
- Q9P2Y5
Target
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