COMMD5 antibody

Catalog No. ABIN5697349

This Rabbit Polyclonal antibody specifically detects COMMD5 in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for COMMD5 antibody (ABIN5697349)

Target: COMMD5 (COMM Domain Containing 5 (COMMD5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-COMMD5 Antibody

Purpose: COMMD5 antibody

Immunogen: COMM domain containing 5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for COMMD5

Target: COMMD5 (COMM Domain Containing 5 (COMMD5))

Alternative Name: COMMD5

Background:

Synonyms: COMM domain-containing protein 5|Hypertension-related calcium-regulated gene protein (HCaRG)|COMMD5

Background: May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed:15799966).

Molecular Weight: 25-28 kDa

Gene ID: 28991

UniProt: Q9GZQ3