SETDB1 antibody

Catalog No. ABIN5697624

The Rabbit Polyclonal anti-SETDB1 antibody (ABIN5697624) specifically detects SETDB1 in WB, ELISA, IHC and IP. The antibody is reactive with Human and Mouse samples.

Quick Overview for SETDB1 antibody (ABIN5697624)

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETDB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-SETDB1 Antibody

Purpose: SETDB1 antibody

Immunogen: SET domain, bifurcated 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07771(SETDB1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SETDB1

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Alternative Name: SETDB1

Background:

Synonyms: Histone-lysine N-methyltransferase SETDB1|ERG-associated protein with SET domain (ESET)|Histone H3-K9 methyltransferase 4 (H3-K9-HMTase 4)|Lysine N-methyltransferase 1E|SET domain bifurcated 1|SETDB1|ESET|KIAA0067|KMT1E

Background: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Gene ID: 9869

UniProt: Q15047