TFEB antibody (AA 43-200)

Catalog No. ABIN5698553

The Rabbit Polyclonal anti-TFEB antibody has been validated for WB, ELISA, IHC, IF and IP. It is suitable to detect TFEB in samples from Human, Mouse and Rat.

Quick Overview for TFEB antibody (AA 43-200) (ABIN5698553)

Target: TFEB (Transcription Factor EB (TFEB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFEB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-TFEB Antibody

Binding Specificity: AA 43-200

Purpose: TFEB antibody

Immunogen:

Immunogen sequence: 43-200aa

Immunogen: transcription factor EB

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08627(TFEB antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Alternative Name: TFEB

Background:

Synonyms: Transcription factor EB|Class E basic helix-loop-helix protein 35 (bHLHe35)|TFEB|BHLHE35

Background: TFEB specifically recognizes and binds to E-box sequences, which required dimerization with itself or another MiT/TFE family member. It plays a role in T-cell-dependent antibody responses to activated CD4+ T-cells and thymus-dependent humoral immunity once associated with TFE3. It also activates lysosomal gene by binding the CLEAR-box sequence in the regulatory region. It involves in the signal transduction processes required for normal vascularization of the placenta. This is a rabbit polyclonal antibody raised against the full length of human TFEB. The calcualted molecular weight of TFEB is 53 kDa, but modified TFEB is about 65-70 kDa.

Gene ID: 7942

UniProt: P19484