WISP1 antibody

Catalog No. ABIN5698715

The Rabbit Polyclonal anti-WISP1 antibody is suitable to detect WISP1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA and IP.

Quick Overview for WISP1 antibody (ABIN5698715)

Target: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WISP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-WISP1 Antibody

Purpose: CCN4 antibody

Immunogen: WNT1 inducible signaling pathway protein 1

Isotype: IgG

Application Details

Application Notes: WB:1:200-1:2000,IHC:1:20-1:200,IP:1:200-1:2000

Comment:

rat kidney tissue were subjected to SDS PAGE followed by western blot with FNab09514( WISP1 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for WISP1

Target: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Alternative Name: CCN4

Background:

Synonyms: CCN family member 4|WNT1-inducible-signaling pathway protein 1 (WISP-1)|Wnt-1-induced secreted protein|CCN4|WISP1

Background: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Molecular Weight: 49kDa

Gene ID: 8840

UniProt: O95388

Pathways: WNT Signaling, Growth Factor Binding