Plexin B2 antibody
Quick Overview for Plexin B2 antibody (ABIN5698971)
Target
See all Plexin B2 (PLXNB2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- PLXNB2 antibody
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Immunogen
- plexin B2
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- Plexin B2 (PLXNB2)
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Alternative Name
- PLXNB2
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Background
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Synonyms: Plexin-B2|MM1|PLXNB2|KIAA0315
Background: Semaphorins, originally identified as axon guidance molecules, have also been implicated in angiogenesis, immunoregulation, and cancer (PMID: 16584533). Plexins are main receptors for semaphorins and are thought to control many of the functional effects of semaphorins. PLXNB2 is one of the three plexin-B family members which participate in axon guidance and cell migration in response to semaphorins. It has been reported that plexin B2 precursor is 240 kDa and can be cleaved into alpha subunit (~170- kDa) and beta subunit (80- kDa) (PMID: 12533544).
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Pathways
- Tube Formation
Target
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