ICAM1 antibody (AA 200-532)

Catalog No. ABIN5699217

This anti-ICAM1 antibody is a Mouse Monoclonal antibody detecting ICAM1 in WB, FACS, IHC and ELISA. Suitable for Human and Rat.

Quick Overview for ICAM1 antibody (AA 200-532) (ABIN5699217)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

Product Details anti-ICAM1 Antibody

Binding Specificity: AA 200-532

Purpose: ICAM1 antibody

Immunogen:

Immunogen sequence: 200-532aa

Immunogen: intercellular adhesion molecule 1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Raji cells were subjected to SDS PAGE followed by western blot with FNab04103( ICAM-1 Antibody) at dilution of 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: ICAM1

Background:

Synonyms: Intercellular adhesion molecule 1 (ICAM-1)|Major group rhinovirus receptor|ICAM1

Background: ICAM-1 (CD54) is a 90- kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451, 9694714, 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624, 2538244, 2475784).

Molecular Weight: 85-95 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling