HOPX antibody

Catalog No. ABIN5699466

This anti-HOPX antibody is a Rabbit Polyclonal antibody detecting HOPX in WB, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for HOPX antibody (ABIN5699466)

Target: HOPX (HOP Homeobox (HOPX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-HOPX Antibody

Immunogen: HOP homeobox

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX

Background: Synonyms:HOD, HOP, LAGY, NECC1, OB1 Background:Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.

Molecular Weight: 8-12 kDa

Gene ID: 84525

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation