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ADAR antibody

This anti-ADAR antibody is a Rabbit Polyclonal antibody detecting ADAR in WB, IHC, ELISA, IF and IP. Suitable for Human, Mouse, Rat and Pig.
Catalog No. ABIN5699808

Quick Overview for ADAR antibody (ABIN5699808)

Target

See all ADAR Antibodies
ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

Reactivity

  • 85
  • 28
  • 23
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Pig

Host

  • 81
  • 5
  • 1
Rabbit

Clonality

  • 73
  • 14
Polyclonal

Conjugate

  • 37
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This ADAR antibody is un-conjugated

Application

  • 57
  • 27
  • 27
  • 21
  • 20
  • 10
  • 9
  • 8
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  • 6
  • 3
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)
  • Immunogen

    adenosine deaminase, RNA-specific

    Isotype

    IgG
  • Application Notes

    WB :1:500-1:5000,IHC:1:20-1:200,IP:1:200-1:2000,IF:1:20-1:200

    Comment

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab00150( ADAR1 Antibody) at dilution of 1:1000

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze / thaw cycles.

    Storage

    -20 °C

    Expiry Date

    12 months
  • Target

    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))

    Alternative Name

    ADAR1

    Background

    Synonyms:ADAR, ADAR1, adenosine deaminase, RNA, DRADA, DSH, DSRAD, G1P1, IFI 4, IFI4, Interferon inducible protein 4, K88dsRBP, p136 Background:ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region(PMID:15556947). The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon(IFN) inducible ?150 kDa protein and a constitutively expressed N-terminally truncated ?110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters(PMID:11111054). It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria(DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities(PMID:17428802).

    Molecular Weight

    136kDa,observed 110kDa

    UniProt

    P55265

    Pathways

    Protein targeting to Nucleus
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