ASNA1 antibody

Catalog No. ABIN5700288

This anti-ASNA1 antibody is a Rabbit Polyclonal antibody detecting ASNA1 in WB, ELISA, IHC, IF, IP and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for ASNA1 antibody (ABIN5700288)

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASNA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-ASNA1 Antibody

Purpose: GET3 antibody

Immunogen: arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab00643(ASNA1 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ASNA1

Target: ASNA1 (ArsA Arsenite Transporter, ATP-Binding, Homolog 1 (ASNA1))

Alternative Name: GET3

Background:

Synonyms: ATPase GET3|Arsenical pump-driving ATPase|Arsenite-stimulated ATPase|Guided entry of tail-anchored proteins factor 3, ATPase|Transmembrane domain recognition complex 40 kDa ATPase subunit|hARSA-I|hASNA-I|GET3|ARSA|ASNA1|TRC40

Background: This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anchored (TA) proteins from the cytosol to the endoplasmic reticulum (ER). It recognizes and selectively binds the TMD of TA proteins in the cytosol, and delivers them to the ER for insertion.

Molecular Weight: 37-41 kDa

Gene ID: 439

UniProt: O43681

Pathways: Positive Regulation of Peptide Hormone Secretion