BAIAP2 antibody
Quick Overview for BAIAP2 antibody (ABIN5700348)
Target
See all BAIAP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- BAI1-associated protein 2
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00793( BAIAP2 Antibody) at dilution of 1:600
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))
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Alternative Name
- BAIAP2
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Background
- Synonyms: Background:The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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Gene ID
- 10458
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UniProt
- Q9UQB8
Target
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