UBE2C antibody

Catalog No. ABIN5700656

The Rabbit Polyclonal anti-UBE2C antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect UBE2C in samples from Human, Mouse and Rat.

Quick Overview for UBE2C antibody (ABIN5700656)

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-UBE2C Antibody

Immunogen: ubiquitin-conjugating enzyme E2C

Isotype: IgG

Application Details

Application Notes: WB :1:200-1:2000,IHC:1:20-1:200,IP:1:10-1:100

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab09165(UBE2C antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for UBE2C

Target: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Alternative Name: UBE2C

Background: Synonyms:DJ447F3.2, UBCH10, UBE2C, Ubiquitin carrier protein C, Ubiquitin protein ligase C Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

Molecular Weight: 17kDa

Gene ID: 11065

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway