POLD1 antibody
Quick Overview for POLD1 antibody (ABIN5700743)
Target
See all POLD1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- POLD1 antibody
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Immunogen
- polymerase (DNA directed), delta 1, catalytic subunit 125kDa
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- POLD1 (Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))
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Alternative Name
- POLD1
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Background
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Synonyms: DNA polymerase delta catalytic subunit|3'-5' exodeoxyribonuclease|DNA polymerase subunit delta p125|POLD1|POLD
Background: This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
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Gene ID
- 5424
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UniProt
- P28340
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Pathways
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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