NAMPT antibody

Catalog No. ABIN5701421

The Rabbit Polyclonal anti-NAMPT antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect NAMPT in samples from Human, Rat, Mouse and Zebrafish (Danio rerio).

Quick Overview for NAMPT antibody (ABIN5701421)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAMPT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-NAMPT Antibody

Immunogen: nicotinamide phosphoribosyltransferase

Isotype: IgG

Application Details

Application Notes: WB :1:500-1:5000,IHC:1:20-1:200,IP:1:500-1:5000

Comment:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09412( NAMPT Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Alternative Name: Visfatin

Background: Synonyms:1110035O14Rik, DKFZp666B131, NAmPRTase, NAMPT, PBEF, PBEF1, Pre B cell enhancing factor, VF, VISFATIN Background:Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Molecular Weight: 47kDa

UniProt: P43490