ADAM12 antibody

Catalog No. ABIN5702017

This Rabbit Polyclonal antibody specifically detects ADAM12 in ELISA, WB, IHC, IF and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for ADAM12 antibody (ABIN5702017)

Target: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM12 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-ADAM12 Antibody

Purpose: ADAM12 antibody

Immunogen: ADAM metallopeptidase domain 12

Isotype: IgG

Application Details

Application Notes: WB :1:500-1:5000,IHC:1:20-1:200,IP:1:200-1:1000,IF:1:10-1:100

Comment:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00137(ADAM12 antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ADAM12

Target: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Alternative Name: ADAM12

Background:

Synonyms: Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12)|Meltrin-alpha|ADAM12|MLTN

Background: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.

Molecular Weight: 100kDa,observed 97kDa,68kDa

Gene ID: 8038

UniProt: O43184

Pathways: EGFR Signaling Pathway