ACADVL antibody (AA 534-578)

Catalog No. ABIN5702030

The Rabbit Polyclonal anti-ACADVL antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect ACADVL in samples from Human, Rat and Mouse.

Quick Overview for ACADVL antibody (AA 534-578) (ABIN5702030)

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADVL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-ACADVL Antibody

Binding Specificity: AA 534-578

Purpose: ACADVL antibody

Immunogen:

Immunogen sequence: 534-578aa

Immunogen: acyl-Coenzyme A dehydrogenase, very long chain

Isotype: IgG

Application Details

Application Notes: WB :1:200-1:2000,IHC:1:20-1:200,IP:1:200-1:2000

Comment:

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab00068(ACADVL antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ACADVL

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Alternative Name: ACADVL

Background:

Synonyms: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD)|ACADVL|VLCAD

Background: Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71- kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.

Molecular Weight: 70kDa,observed 98kDa and 51kDa

Gene ID: 37

UniProt: P49748

Pathways: ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process