E2F3 antibody

Catalog No. ABIN5702264

The Rabbit Polyclonal anti-E2F3 antibody is suitable to detect E2F3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IP.

Quick Overview for E2F3 antibody (ABIN5702264)

Target: E2F3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-E2F3 Antibody

Purpose: E2F3 antibody

Immunogen: E2F transcription factor 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for E2F3

Target: E2F3

Background:

Synonyms: Transcription factor E2F3 (E2F-3)|E2F3|KIAA0075

Background: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters(By similarity).

Molecular Weight: 52 kDa

Gene ID: 1871

UniProt: O00716