SERPINH1 antibody

Catalog No. ABIN5702324

The Rabbit Polyclonal anti-SERPINH1 antibody has been validated for WB, ELISA, IHC, IF and FACS. It is suitable to detect SERPINH1 in samples from Human, Mouse and Rat.

Quick Overview for SERPINH1 antibody (ABIN5702324)

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-SERPINH1 Antibody

Immunogen: serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

Isotype: IgG

Application Details

Application Notes: WB : 1:200-1:1000 IHC : 1:20-1:200 IF : 1:10-1:100

Comment:

HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab04045(SERPINH1 antibody) at dilution of 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for SERPINH1

Target: SERPINH1 (Serpin Family H Member 1 (SERPINH1))

Alternative Name: HSP47

Background: Synonyms:47 kDa heat shock protein, AsTP3, CBP1, CBP2, Collagen binding protein, Colligin, gp46, HSP47, PIG14, PPROM, RA A47, Serpin H1, SERPINH1, SERPINH2 Background:This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Molecular Weight: 46-48 kDa

UniProt: P50454