EYA3 antibody

Catalog No. ABIN5702789

The Rabbit Polyclonal anti-EYA3 antibody has been validated for WB, IHC, ELISA, IF and IP. It is suitable to detect EYA3 in samples from Human, Mouse and Rat.

Quick Overview for EYA3 antibody (ABIN5702789)

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-EYA3 Antibody

Purpose: EYA3 antibody

Immunogen: eyes absent homolog 3 (Drosophila)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab02915( EYA3 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3

Background:

Synonyms: Eyes absent homolog 3|EYA3

Background: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.

Molecular Weight: 63-66 kDa

Gene ID: 2140

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus