IGF2BP3 antibody

Catalog No. ABIN5703016

This Rabbit Polyclonal antibody specifically detects IGF2BP3 in WB, IHC, ELISA, IP and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for IGF2BP3 antibody (ABIN5703016)

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2BP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-IGF2BP3 Antibody

Purpose: IGF2BP3 antibody

Immunogen: insulin-like growth factor 2 mRNA binding protein 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04173(IGF2BP3 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IGF2BP3

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Alternative Name: IGF2BP3

Background:

Synonyms: Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3, IMP-3)|IGF-II mRNA-binding protein 3|KH domain-containing protein overexpressed in cancer (hKOC)|VICKZ family member 3|IGF2BP3|IMP3|KOC1|VICKZ3

Background: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Molecular Weight: 64 kDa

Gene ID: 10643

UniProt: O00425