LIMS1 antibody
Quick Overview for LIMS1 antibody (ABIN5703373)
Target
See all LIMS1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- LIM and senescent cell antigen-like domains 1
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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human kidney tissue were subjected to SDS PAGE followed by western blot with FNab04782(LIMS1 antibody) at dilution of 1:400
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- LIMS1 (LIM and Senescent Cell Antigen-Like Domains 1 (LIMS1))
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Alternative Name
- LIMS1
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Background
- Synonyms:PINCH, PINCH1 Background:The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 35-37 kDa
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Gene ID
- 3987
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UniProt
- P48059
Target
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