HPS4 antibody

Catalog No. ABIN5703646

This Rabbit Polyclonal antibody specifically detects HPS4 in WB, IHC, IP, IF and ELISA. It exhibits reactivity toward Human.

Quick Overview for HPS4 antibody (ABIN5703646)

Target: HPS4 (Hermansky-Pudlak Syndrome 4 (HPS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPS4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), ELISA

Product Details anti-HPS4 Antibody

Purpose: HPS4 antibody

Immunogen: Hermansky-Pudlak syndrome 4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

A375 cells were subjected to SDS PAGE followed by western blot with FNab04000(HPS4 antibody) at dilution of 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HPS4

Target: HPS4 (Hermansky-Pudlak Syndrome 4 (HPS4))

Alternative Name: HPS4

Background:

Synonyms: BLOC-3 complex member HPS4|Hermansky-Pudlak syndrome 4 protein|Light-ear protein homolog|HPS4|KIAA1667

Background: Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor(GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38(PubMed:23084991).

Molecular Weight: 70 kDa and 90 kDa

Gene ID: 89781

UniProt: Q9NQG7