DDX39B antibody

Catalog No. ABIN5703741

This anti-DDX39B antibody is a Rabbit Polyclonal antibody detecting DDX39B in ELISA, IHC, WB and IP. Suitable for Human, Mouse and Rat.

Quick Overview for DDX39B antibody (ABIN5703741)

Target: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX39B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DDX39B Antibody

Immunogen: HLA-B associated transcript 1

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200

Comment:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09142(BAT1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for DDX39B

Target: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Alternative Name: UAP56

Background: Synonyms:ATP dependent RNA helicase p47, BAT1, D6S81E, DDX39B, DEAD box protein UAP56, HLA B associated transcript 1, Spliceosome RNA helicase BAT1, UAP56 Background:This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13 kDa, V1 subunit G2) gene.

Molecular Weight: 57kDa

UniProt: Q13838

Pathways: Ribonucleoprotein Complex Subunit Organization