YAP1 antibody
Quick Overview for YAP1 antibody (ABIN5704560)
Target
See all YAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- Yes-associated protein 1, 65kDa
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Isotype
- IgG
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Application Notes
- WB:1:500-1:5000,IHC:1:50-1:200,IF:1:20-1:200,IP:1:200-1:2000
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Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09559( YAP1 Antibody) at dilution of 1:1000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- YAP1 (Yes-Associated Protein 1 (YAP1))
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Alternative Name
- YAP1
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Background
- Synonyms:65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog Background:This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 108kDa
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Gene ID
- 10413
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UniProt
- P46937
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Pathways
- MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Target
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